What is the normal reference range for total protein in serum?

What is the normal reference range for total protein in serum?

• A. 6.5-8.5 g/dL
• B. 4.5-7.0 g/dL
• C. 5.0-7.5 g/dL
• D. 7.0-9.0 g/dL

Answer: (A)

Total serum protein reflects the sum of albumin and globulin proteins in the blood. In healthy adults these proteins typically add up to about 6.5–8.5 g/dL, so this range is used as the reference interval. Labs may differ slightly (some cite 6.0–8.0 or 6.0–8.3 g/dL) due to different methods or population standards, but values outside roughly 6 g/dL on the low side or above about 8.5–9 g/dL on the high side suggest abnormal protein status and merit further evaluation. The other ranges provided would place a healthy person outside the common reference window.

Total serum protein reflects the sum of albumin and globulin proteins in the blood. In healthy adults these proteins typically add up to about 6.5–8.5 g/dL, so this range is used as the reference interval. Labs may differ slightly (some cite 6.0–8.0 or 6.0–8.3 g/dL) due to different methods or population standards, but values outside roughly 6 g/dL on the low side or above about 8.5–9 g/dL on the high side suggest abnormal protein status and merit further evaluation. The other ranges provided would place a healthy person outside the common reference window.